George Nicholas Papanicolaou was born in Kimi on the island of Euboea. It is near the southern town of Karystos known for the ancient physician Diokles of. Even at a young age, George Papanicolaou envisioned himself striving to live his life out on some large, important, but as yet undefined stage. After receiving his. Georgios Nikolaou Papanikolaou was a Greek pioneer in cytopathology and early cancer George Papanikolaou In he moved to Miami, Florida, to develop the Papanicolaou Cancer Research Institute at the University of Miami, but.

Author: JoJolrajas Tojanris
Country: Botswana
Language: English (Spanish)
Genre: Environment
Published (Last): 28 June 2013
Pages: 79
PDF File Size: 16.58 Mb
ePub File Size: 15.61 Mb
ISBN: 611-7-14110-498-5
Downloads: 88140
Price: Free* [*Free Regsitration Required]
Uploader: Mazilkree

George Nicholas Papanicolaou Greek-American Physician G eorge Nicholas Papanicolaou was the originator of the Pap test used in the diagnosis of cervical cancer.

The history of the Papanicolaou smear and the odyssey of George and Andromache Papanicolaou. He was the recipient of numerous nkcholas, including honorary degrees from universities in the US, Italy and Greece.

Shortly thereafter, inhe published Atlas of Exfoliative Cytology papanciolaou, a treatise containing comprehensive information on the cytology of both healthy and diseased tissue, not just in the female reproductive system but also in other organ georbe.

Papanicolaou Society of Cytopathology. Recent papers have proven that Babes’s method was different from Papanicolaou’s and that the paternity of Pap test belongs solely to Papanicolaou. Learn more about citation styles Citation styles Encyclopedia. Highlight search term Save Cite Email Share.

For the next two years, he cared for leprosy patients on the outskirts of his hometown. The Pap smear Papanicolaou is best known for his development of the “Pap test,” for the cytologic diagnosis of cancer, especially cancer of the uterus – second only to the breast as the site of origin of fatal cancers in American women.

Papanicolaou first reported in that he could recognise cancer cells but georte importance of his findings was not generally accepted and he abandoned the work for some years. New York,p During these studies Papanicolaou noted cyclical changes in various vaginal discharges from test animals that Papanicolaou linked gdorge the ovarian and uterine cycles.


The fact that malignant cells could be seen georgd the microscope was first pointed out in a nicholxs on diseases of the lung, by Walter Hayle Walshe —92professor and physician to University College Hospital, London, in Parthenon Publishing Group; Papanicolaou persisted with his ideas, and finally cytologic examination of the cervix was accepted. University of Athens University of Munich. Fromhe began to focus on the cytopathology of the human reproductive system. Inhe graduated from medical school with top honours.

Although his initial publication of the finding in went largely unnoticed, that year was filled with other happy events for Papanicolaou. Papanikolaou’s portrait appeared on the obverse of the Greek 10, drachma banknote of —, [9] prior to its replacement by the euro. Other diagnostic tests based upon Papanicolaou’s methodology exfoliated cytology, the scraping, staining, and examination of cells from the test site proved effective in screening for abnormalities in cells from other organs and systems.

As part of his research at the New York Hospital, he collaborated with Dr Ncholas Traut, a gynaecological pathologist, eventually publishing their landmark book inDiagnosis of Uterine Cancer by the Vaginal Smear.

Four books and over articles Parents: Retrieved December 31, from Encyclopedia. George Nicholas Papanicolaou Artist: During the Balkan War,he served as second lieutenant in the medical corps of the Greek army, fighting the Turks. In the ‘s, George Papanicolaou began to publish his studies on the structure, function, and transformation of cells as viewed under a microscope a branch georhe biology known as cytology.

Papanicolaou was nichollas on May the 13, in the city of Kymi on the Greek geotge of Euboea. The institute was renamed the Papanicolaou Cancer Research Institute in his honor.

George Nicholas Papanicolaou |

Even in retirement, Papanicolaou proved restless: As a boy he loved outdoor life, particularly mountain hiking av boating. He worked for one year as a physiologist and then returned to Greece upon the death of his mother. After nearly a half-century of research at Cornell, Papanicolaou retired with his beloved wife to Florida. In female guinea pigs, Papanicolaou had already noticed cell transformation and wanted to corroborate the phenomenon in human females.


Georgios Papanikolaou

Support Center Geoege Center. After receiving his M. After graduation, Papanicolaou worked in the military as an assistant surgeon for a short time, then returned to his hometown, Kimi.

Papanicolaou’s early work studied the role of chromosomes in sex determination. George Nicholas Papanicolaou was born in Kimi on the island of Euboea. Papanicolaou was not the first to show that cancerous cells could be identified under the microscope. In countries where Pap smears are routine clinical practice, cervical cancer rates have dropped dramatically, and the screening test pxpanicolaou credited as one of the greatest life-saving techniques in medical practice.

Author information Copyright and License information Disclaimer.

[George Nicholas Papanicolaou].

His image was featured on the Greek 10,drachma currency note prior to its replacement by the euro and on various Greek stamps. Moreover, the two techniques are different in their design. During his research Papanicolaou observed that smears from women who had been diagnosed with cervical cancer showed cellular abnormalities enlarged, deformed, or hyperchromatic nuclei.

He subsequently researched the human female menstrual cycle cytology and used his techniques to examine cells for cancer in ; he then presented and published about the same thing in humans in —to a skeptical audience of surgeons. A screening test for the prevention of cancer of uterine cervix. Sign in with your library card. By January research had begun but unfortunately he suffered a heart attack in February and died, three months after moving to Miami. In —with a new wife and no firm prospects—Papanicolaou set sail for America.

Diagnosis of Uterine Cancer by the Vaginal Smear.

Ultimately, the Pap smear became a routine, clinical diagnostic test. The diagnostic value of vaginal smears in carcinoma of the uterus. Therefore, although Babes publication preceded Papanicolaou, the design of the Pap test belongs to Papanicolaou since he had already tried it in in “Women’s Hospital”.